Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 2/20 | 0.34 |
| ▸ | ACE | P12821 | 2/20 | 0.34 |
| ▸ | CPA1 | P15085 | 2/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12538270 | 1.00 | CYP2D6 (0.36) | CYP2D6CYP2C19ALDH1A1TSHRMMP1 | |
| SCHEMBL16165794 | 1.00 | CYP2D6 (0.36) | CYP2D6CYP2C19ALDH1A1TSHRMMP1 | |
| SCHEMBL28709188 | 0.85 | CYP2D6 (0.36) | CYP2D6CYP2C19ALDH1A1TSHRMMP1 | |
| SCHEMBL6722400 | 0.83 | TAS1R3 (0.42) | CYP2D6CYP2C19ALDH1A1MMP1MMP2 | |
| SCHEMBL11753460 | 0.82 | CHRM1 (0.39) | CYP2D6CYP2C19ALDH1A1TSHRTAS1R3 | |
| SCHEMBL25173479 | 0.81 | PAX8 (0.38) | CYP2D6CYP2C19MMETP53MEN1 | |
| SCHEMBL20572594 | 0.81 | PAX8 (0.38) | CYP2D6CYP2C19MMETP53MEN1 | |
| SCHEMBL20644467 | 0.81 | ALDH1A1 (0.39) | CYP2D6CYP2C19ALDH1A1TSHRMMP1 | |
| SCHEMBL21126128 | 0.81 | ALDH1A1 (0.39) | CYP2D6CYP2C19ALDH1A1TSHRMMP1 | |
| SCHEMBL16165376 | 0.81 | ALDH1A1 (0.31) | CYP2D6CYP2C19ALDH1A1TSHRMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675141-B2 | Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof | UNION CARBIDE CHEM PLASTIC (US) | 2004-09-29 | — | — | EP | claimed |
| EP-0675141-B1 | Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof | UNION CARBIDE CHEM PLASTIC (US) | 1998-06-03 | — | — | EP | claimed |
| EP-0675141-A1 | Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1995-10-04 | — | — | EP | claimed |
| US-5412049-A | Polymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1995-05-02 | — | — | US | claimed |
| US-4062889-A | Preparation of sulfonylureas | ERIC LUCIEN | 1977-12-13 | — | — | US | claimed |
| EP-1362067-B1 | DURABLE REFINISH COATING | BASF CORP (US) | 2011-03-30 | — | — | EP | disclosed |
| EP-1503749-A4 | METHIONINE AMINOPEPTIDASE-2 INHIBITORS AND METHODS OF USE THEREOF | PRAECIS PHARM INC (US) | 2008-04-09 | — | — | EP | disclosed |
| WO-2008011114-A2 | METHIONINE AMINOPEPTIDASE-2 INHIBITORS AND METHODS OF USE THEREOF | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2008-01-24 | — | — | WO | disclosed |
| EP-1503749-A2 | METHIONINE AMINOPEPTIDASE-2 INHIBITORS AND METHODS OF USE THEREOF | Praecis Pharmaceuticals Inc. (US) | 2005-02-09 | — | — | EP | disclosed |
| EP-0675141-B2 | Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof | UNION CARBIDE CHEM PLASTIC (US) | 2004-09-29 | — | — | EP | disclosed |
| EP-1362067-A2 | COATING | Basf Corporation (US) | 2003-11-19 | — | — | EP | disclosed |
| WO-2003092608-A2 | METHIONINE AMINOPEPTIDASE-2 INHIBITORS AND METHODS OF USE THEREOF | PRAECIS PHARMACEUTICALS, INC. (US) | 2003-11-13 | — | — | WO | disclosed |
| WO-2002050199-A2 | COATING | BASF CORPORATION, PLEASE SEE GENERAL APPOINTMENT OF REPRESENTATIVE (US) | 2002-06-27 | — | — | WO | disclosed |
| WO-2002042295-A2 | PEPTIDES AS MET-AP2 INHIBITORS | PRAECIS PHARMACEUTICALS INC. (US) | 2002-05-30 | — | — | WO | disclosed |
| US-5945499-A | High solids thermosetting compositions with dual cure mechanism | BASF CORPORATION (US) | 1999-08-31 | — | — | US | disclosed |
| US-5907024-A | CURABLE COATING SOLUTION CONTAINING A COMPOUND HAVING HYDROXYL AND CARBAMATE FUNCTIONALITY, A POLYISOCYANATE CROSSLINKER AND AN AMINOPLAST CROSSLINKER; COATING THE STEEL PANEL WITH ABOVE SOLUTION AND CURING WITHOUT SAGGING | BASF CORPORATION (US) | 1999-05-25 | — | — | US | disclosed |
| EP-0915113-A1 | High solids thermosetting compositions with dual cure mechanism | BASF CORPORATION (US) | 1999-05-12 | — | — | EP | disclosed |
| EP-0675141-B1 | Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof | UNION CARBIDE CHEM PLASTIC (US) | 1998-06-03 | — | — | EP | disclosed |
| EP-0675141-A1 | Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1995-10-04 | — | — | EP | disclosed |
| US-5412049-A | Polymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1995-05-02 | — | — | US | disclosed |