Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14374231 | 0.89 | MAPK1 (0.39) | HTR2CHTR2AHTR2BMAT2AADORA3 | |
| SCHEMBL14347562 | 0.81 | HTR2A (0.36) | HTR2CHTR2AHTR2BHIPK2ADORA3 | |
| SCHEMBL14374782 | 0.74 | PDE10A (0.41) | HTR2CHTR2AHTR2BMAT2AMAPT | |
| SCHEMBL14374643 | 0.74 | CCR1 (0.40) | HTR2CHTR2AHTR2BMAT2AMAPK1 | |
| SCHEMBL14374177 | 0.71 | DYRK1A (0.38) | HTR2CHTR2AHTR2BHIPK2ADORA3 | |
| SCHEMBL14374967 | 0.70 | CYP1A2 (0.35) | HTR2CHTR2AHTR2BHIPK2DYRK1A | |
| SCHEMBL14347542 | 0.69 | ROCK2 (0.36) | HTR2CHTR2AHTR2BADORA3ADORA2A | |
| SCHEMBL25703670 | 0.68 | TOP2A (0.54) | HTR2CHTR2AHTR2BTOP2AMAPT | |
| SCHEMBL23169453 | 0.67 | PDE3B (0.42) | HTR2CHTR2AHTR2BDYRK1ACLK1 | |
| SCHEMBL14374602 | 0.65 | MAT2A (0.49) | MAT2AMAPK1RORCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312211-B2 | Pryanone compounds useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2007-12-25 | — | — | US | disclosed |