Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.53 |
| ▸ | SLC18A2 | Q05940 | 3/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12592383 | 1.00 | SLC6A3 (0.53) | SLC6A3SLC18A2CHRM2CHRM4CHRM5 | |
| SCHEMBL13473847 | 1.00 | SLC6A3 (0.53) | SLC6A3SLC18A2CHRM2CHRM4CHRM5 | |
| SCHEMBL13473844 | 1.00 | SLC6A3 (0.53) | SLC6A3SLC18A2CHRM2CHRM4CHRM5 | |
| SCHEMBL14065598 | 0.91 | MAPT (0.54) | SLC6A3SLC18A2CHRM2CHRM4CHRM5 | |
| SCHEMBL14376312 | 0.91 | MAPT (0.54) | SLC6A3SLC18A2CHRM2CHRM4CHRM5 | |
| SCHEMBL14065593 | 0.91 | MAPT (0.54) | SLC6A3SLC18A2CHRM2CHRM4CHRM5 | |
| SCHEMBL14371524 | 0.83 | SLC6A2 (0.49) | SLC6A3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL12592377 | 0.83 | SLC6A2 (0.49) | SLC6A3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL12592372 | 0.83 | SLC6A2 (0.49) | SLC6A3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL13473846 | 0.83 | SLC6A2 (0.49) | SLC6A3CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276520-B2 | Bicyclic piperidine derivatives as melanocortin-4 receptor agonists | MERCK & CO., INC. (US) | 2007-10-02 | — | — | US | disclosed |