Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8381207 | 0.83 | LMNA (0.38) | LMNAMEN1KMT2AGAATSHR | |
| SCHEMBL4704005 | 0.83 | TSHR (0.48) | LMNAALDH1A1TSHR | |
| SCHEMBL8381205 | 0.82 | LMNA (0.37) | LMNAMEN1KMT2AGAATSHR | |
| SCHEMBL14355272 | 0.80 | ALDH1A1 (0.38) | PAOXLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL14707175 | 0.79 | MEN1 (0.42) | LMNAMEN1KMT2AALDH1A1ACHE | |
| SCHEMBL25683396 | 0.79 | PAOX (0.40) | PAOXLMNAALDH1A1ACHECHRM1 | |
| SCHEMBL6256081 | 0.79 | HDAC6 (0.40) | PAOXALDH1A1ACHEGAA | |
| SCHEMBL8064652 | 0.78 | ALDH1A1 (0.41) | LMNAALDH1A1ACHE | |
| SCHEMBL22203118 | 0.78 | LMNA (0.44) | PAOXLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL22282294 | 0.78 | LMNA (0.40) | LMNAMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276017-A1 | Thiadiazoline Derivative | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276017-A1 | Thiadiazoline Derivative | BRD7, NR3C2, NR5A2 | PAOX 3546/4885LMNA 4447/4885MEN1 2331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.