Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8383339 | 0.94 | LMNA (0.41) | LMNAMEN1KMT2AGAATSHR | |
| SCHEMBL8381762 | 0.92 | LMNA (0.43) | LMNAMEN1KMT2AFAAHTP53 | |
| SCHEMBL8384869 | 0.89 | MEN1 (0.39) | LMNAMEN1KMT2AGAATSHR | |
| SCHEMBL4704005 | 0.83 | TSHR (0.48) | LMNATSHR | |
| SCHEMBL14379958 | 0.83 | PAOX (0.43) | LMNAMEN1KMT2AGAATSHR | |
| SCHEMBL8381205 | 0.82 | LMNA (0.37) | LMNAMEN1KMT2AGAATSHR | |
| SCHEMBL25571626 | 0.81 | CHRNB2 (0.36) | LMNAMEN1KMT2AFAAHTP53 | |
| SCHEMBL8383399 | 0.80 | ALOX15 (0.41) | LMNAMEN1KMT2AGAANOS3 | |
| SCHEMBL14707175 | 0.79 | MEN1 (0.42) | LMNAMEN1KMT2AGAATSHR | |
| SCHEMBL9219474 | 0.79 | HDAC6 (0.40) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |