SCHEMBL14380296

Cc1ccn(-c2c3c(c(-n4ccc(C)n4)c(-n4ccc(C)n4)c2-n2ccc(C)n2)-c2nccnc2-c2c(c(-n4ccc(C)n4)c(-n4ccc(C)n4)c(-n4ccc(C)n4)c2-n2ccc(C)n2)-c2nccnc2-3)n1

nearest known ligand 0.43

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	MAPT	P10636	2/20	0.43

▸	RAB9A	P51151	2/20	0.43

▸	NPC1	O15118	1/20	0.43

▸	ATM	Q13315	1/20	0.43

▸	SMN1; SMN2	Q16637	1/20	0.43

▸	L3MBTL1	Q9Y468	1/20	0.43

▸	KDM4E	B2RXH2	1/20	0.42

▸	ALDH1A1	P00352	1/20	0.42

▸	GAA	P10253	1/20	0.42

▸	TDO2	P48775	1/20	0.37

▸	HTT	P42858	1/20	0.37

▸	ADORA2A	P29274	2/20	0.32

▸	NOS1	P29475	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14380297	0.78	—	—
SCHEMBL14380299	0.74	PRMT6 (0.39)	MAPTRAB9ANPC1HTT
SCHEMBL13514001	0.68	RAB9A (0.53)	MAPTRAB9ANPC1ATMSMN1; SMN2
SCHEMBL16202103	0.68	MAPT (0.47)	MAPTRAB9ANPC1ATMSMN1; SMN2
SCHEMBL16202101	0.65	RAB9A (0.55)	MAPTRAB9ANPC1ATMSMN1; SMN2
SCHEMBL1813753	0.65	RAB9A (0.55)	MAPTRAB9ANPC1ATMSMN1; SMN2
SCHEMBL1425387	0.64	HTT (0.53)	MAPTRAB9ANPC1ATMSMN1; SMN2
SCHEMBL16201995	0.64	MAPT (0.47)	MAPTRAB9ANPC1ATMSMN1; SMN2
SCHEMBL1907360	0.64	MAPT (0.63)	MAPTRAB9ANPC1ATMSMN1; SMN2
SCHEMBL15935008	0.64	MAPT (0.44)	MAPTRAB9ANPC1ATMSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-7282276-B2	Organic electroluminescent device	FUJIFILM CORPORATION (JP)	2007-10-16	—	—	US	disclosed