Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | MTOR | P42345 | 2/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.44 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38651177 | 1.00 | MAPT (0.63) | MAPTSMN1; SMN2RAB9ANPC1ATM | |
| SCHEMBL13514001 | 0.78 | RAB9A (0.53) | MAPTSMN1; SMN2RAB9ANPC1ATM | |
| SCHEMBL197523 | 0.78 | MAPT (1.00) | MAPTSMN1; SMN2RAB9ANPC1ATM | |
| SCHEMBL19119928 | 0.77 | GRM5 (0.46) | MAPTSMN1; SMN2RAB9ANPC1ATM | |
| SCHEMBL2643353 | 0.77 | GRM5 (0.46) | MAPTSMN1; SMN2RAB9ANPC1ATM | |
| SCHEMBL2160327 | 0.77 | MPO (0.46) | MAPTSMN1; SMN2MTORGRM5GRIA1 | |
| SCHEMBL28076029 | 0.77 | GRM5 (0.46) | MAPTSMN1; SMN2RAB9ANPC1ATM | |
| SCHEMBL29563483 | 0.77 | MPO (0.46) | MAPTSMN1; SMN2MTORGRM5GRIA1 | |
| SCHEMBL3156955 | 0.77 | GRM5 (0.46) | MAPTSMN1; SMN2RAB9ANPC1ATM | |
| SCHEMBL8086526 | 0.77 | GRM5 (0.46) | SMN1; SMN2RAB9AMTORGRM5GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0389189-B1 | Diazepine antiallergy agents | PFIZER LTD (GB) | 1994-05-18 | — | — | EP | claimed |
| US-5008263-A | Platelet activating factor antagonists; antiallergens; antiinflammatory agents | PFIZER INC. (US) | 1991-04-16 | — | — | US | claimed |
| EP-0389189-A2 | Diazepine antiallergy agents | Pfizer Limited (GB) | 1990-09-26 | — | — | EP | claimed |
| EP-3400220-B1 | PYRAZOLE DERIVATIVES | HUA MEDICINE SHANGHAI LTD (CN) | 2021-03-24 | — | — | EP | disclosed |
| EP-2678346-B9 | METAL COMPLEXES FOR USE AS DOPANTS AND OTHER USES | ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) | 2018-08-08 | — | — | EP | disclosed |
| US-10038150-B2 | Metal complexes for use as dopants and other uses | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2018-07-31 | — | — | US | disclosed |
| EP-2678346-B1 | METAL COMPLEXES FOR USE AS DOPANTS AND OTHER USES | ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) | 2018-04-04 | — | — | EP | disclosed |
| US-9779879-B2 | Redox couple for electrochemical and optoelectronic devices | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2017-10-03 | — | — | US | disclosed |
| WO-2017117708-A1 | PYRAZOLE DERIVATIVES | HUA MEDICINE (SHANGHAI) LTD. (CN) | 2017-07-13 | — | — | WO | disclosed |
| US-9559321-B2 | Metal complexes for use as dopants and other uses | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2017-01-31 | — | — | US | disclosed |
| US-20160233439-A1 | METAL COMPLEXES FOR USE AS DOPANTS AND OTHER USES | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) EPFL-TTO (CH) | 2016-08-11 | — | — | US | disclosed |
| EP-2233493-A1 | Macrolides | Pfizer Products Inc. (US) | 2010-09-29 | — | — | EP | disclosed |
| EP-1836211-B1 | MACROLIDES | PFIZER PROD INC (US) | 2010-03-03 | — | — | EP | disclosed |
| WO-2010017047-A1 | THERAPEUTIC COMPOUNDS | MERCK & CO., INC. (US) | 2010-02-11 | — | — | WO | disclosed |
| CN-1322254-A | Small volume in vitro analytical sensor containing diffusible or non-leachable redox mediator | THERASENSE INC (US) | 2001-11-14 | — | — | CN | disclosed |
| EP-0389189-B1 | Diazepine antiallergy agents | PFIZER LTD (GB) | 1994-05-18 | — | — | EP | disclosed |
| US-5008263-A | Platelet activating factor antagonists; antiallergens; antiinflammatory agents | PFIZER INC. (US) | 1991-04-16 | — | — | US | disclosed |
| EP-0389189-A2 | Diazepine antiallergy agents | Pfizer Limited (GB) | 1990-09-26 | — | — | EP | disclosed |
| US-4881965-A | CONTROLLING WILD OATS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1989-11-21 | — | — | US | disclosed |
| EP-0318602-A1 | Pyrazolesulfonamide derivative, process for its production and herbicide containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10038150-B2 | Metal complexes for use as dopants and other uses | SOD1, DDT, SOD3 | MAPT 3516/4885SMN1; SMN2 2031/4885RAB9A 1331/4885 |
| US-20160233439-A1 | METAL COMPLEXES FOR USE AS DOPANTS AND OTHER USES | SOD1, DDT, SOD3 | MAPT 3516/4885SMN1; SMN2 2031/4885RAB9A 1331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.