Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 18/20 | 0.48 |
| ▸ | FAAH | O00519 | 9/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3694422 | 0.77 | MGLL (0.59) | MGLLFAAHHSP90AA1PKMMAPK1 | |
| SCHEMBL10960203 | 0.77 | MGLL (0.48) | MGLLFAAHHSP90AA1PKMMAPK1 | |
| SCHEMBL10585998 | 0.74 | MGLL (0.57) | MGLLFAAHHSP90AA1PKMMAPK1 | |
| SCHEMBL15758246 | 0.73 | MGLL (0.53) | MGLLFAAHHSP90AA1PKMMAPK1 | |
| SCHEMBL3180754 | 0.73 | TSHR (0.54) | MGLLFAAHHSP90AA1PKMMAPK1 | |
| SCHEMBL30645224 | 0.73 | MGLL (0.53) | MGLLFAAHHSP90AA1PKMMAPK1 | |
| SCHEMBL10884128 | 0.72 | G6PD (0.62) | MGLLFAAHHSP90AA1PKMMAPK1 | |
| SCHEMBL10880929 | 0.71 | CCR6 (0.54) | MGLLFAAHHSP90AA1PKMMAPK1 | |
| SCHEMBL10587190 | 0.71 | MGLL (0.57) | MGLLFAAHHSP90AA1PKMMAPK1 | |
| SCHEMBL1258213 | 0.70 | MGLL (0.65) | MGLLFAAHHSP90AA1PKMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1854798-A2 | Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function | Bristol-Myers Squibb Company (US) | 2007-11-14 | — | — | EP | disclosed |