SCHEMBL143822

SCHEMBL143822

[CH2]C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.36
CA2 P00918 2/20 0.33
CA1 P00915 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6655835 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL147573 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL503984 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL954243 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL1828060 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL958058 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL216042 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL5491848 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL445081 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL5492172 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 385 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115746287-B Perfluoro polyether silane compound containing benzene ring structure, preparation method thereof, surface treating agent based on compound and film 苏州东杏表面技术有限公司 2023-05-05 CN claimed
CN-115746287-A Perfluoropolyether silane compound containing benzene ring structure, preparation method thereof, surface treating agent based on compound and film 苏州东杏表面技术有限公司 2023-03-07 CN claimed
EP-3898942-A1 NANOPARTICLE COMPOSITIONS FOR EFFICIENT NUCLEIC ACID DELIVERY AND METHODS OF MAKING AND USING THE SAME Tiba Biotech LLC (US) 2021-10-27 EP claimed
WO-2020132196-A1 NANOPARTICLE COMPOSITIONS FOR EFFICIENT NUCLEIC ACID DELIVERY AND METHODS OF MAKING AND USING THE SAME TIBA BIOTECH LLC (US) 2020-06-25 WO claimed
EP-2532663-B1 Naphthalenetetracarboxylic acid derivatives and their use as semiconductors BASF SE (DE) 2016-03-16 EP claimed
WO-2016004195-A1 HYDROPHOBIC COATING COMPOSITION COMPRISING ALKOXY SILANE MONOMER AND FLUORINATED MONOMER IN AN ORGANIC SOLVENT CYTONIX, LLC (US) 2016-01-07 WO claimed
EP-2532663-A1 Naphthalenecarboxylic acid derivatives and their use as semiconductors BASF SE (DE) 2012-12-12 EP claimed
EP-0497369-B1 Contact lens material and contact lens HOYA CORP (JP) 1997-04-02 EP claimed
US-5264465-A Perfluoroalkylalkoxyalkyl (meth)acrylate copolymers with amide monomers HOYA CORPORATION (JP) 1993-11-23 US claimed
EP-0497369-A2 Contact lens material and contact lens HOYA CORPORATION (JP) 1992-08-05 EP claimed
US-4945139-A SOLVENT RESISTANCE, POLYPHOSPHAZINES ETHYL CORPORATION (US) 1990-07-31 US claimed
CN-113376962-B Coloring composition and compound 住友化学株式会社 2024-05-28 CN disclosed
CN-113376963-B Coloring composition and compound 住友化学株式会社 2024-05-28 CN disclosed
CN-113376965-B Coloring composition and compound 住友化学株式会社 2024-05-28 CN disclosed
US-11993578-B2 Pyrazole-3-carboxylic acid amide derivative and pest control agent KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-05-28 US disclosed
EP-0381005-A2 Ocular lens material Menicon Co., Ltd. (JP) 1990-08-08 EP disclosed
EP-0379146-A2 Soft ocular lens material Menicon Co., Ltd. (JP) 1990-07-25 EP disclosed
EP-0138504-B1 STEROID DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-07-20 EP disclosed
US-4659516-A ANTIESTROGENS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-04-21 US disclosed
EP-0138504-A2 Steroid derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-04-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11993578-B2 Pyrazole-3-carboxylic acid amide derivative and pest control agent H1-3, HDAC3, H1-0 LMNA 4131/4885THRB 1472/4885CA2 275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.