SCHEMBL216042

SCHEMBL216042

[CH2]C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.36
CA2 P00918 2/20 0.33
CA1 P00915 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6655835 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL147573 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL503984 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL954243 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL1828060 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL958058 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL5491848 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL445081 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL5492172 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL143822 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113376965-B Coloring composition and compound 住友化学株式会社 2024-05-28 CN disclosed
CN-113376963-B Coloring composition and compound 住友化学株式会社 2024-05-28 CN disclosed
CN-113376962-B Coloring composition and compound 住友化学株式会社 2024-05-28 CN disclosed
CN-113376964-B Coloring composition and compound 住友化学株式会社 2024-04-26 CN disclosed
US-20240132646-A1 COMPOSITION CONTAINING (METH)ACRYLAMIDE COMPOUND AND COMPOUND HAVING POLYOXYALKYLENE CHAIN RESONAC CORPORATION (JP) 2024-04-25 US disclosed
US-20240132645-A1 COMPOSITION CONTAINING COMPOUND HAVING POLYOXYALKYLENE CHAIN AND COMPOUND HAVING POLY(METH)ACRYLATE CHAIN RESONAC CORPORATION (JP) 2024-04-25 US disclosed
US-20240043648-A1 COMPOSITION AND SHEET CONTAINING CURED PRODUCT OF SAME RESONAC CORPORATION (JP) 2024-02-08 US disclosed
US-20240043597-A1 COMPOSITION AND SHEET RESONAC CORPORATION (JP) 2024-02-08 US disclosed
US-20240047230-A1 METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE RESONAC CORPORATION (JP) 2024-02-08 US disclosed
WO-2024009895-A1 COMPOSITION CONTAINING (METH)ACRYLIC POLYMER AND METAL PARTICLES 株式会社レゾナック 2024-01-11 WO disclosed
US-5110703-A Particles of magnetic powder in binder resin blend of polyolefin and olefin polymer having functional group FUJI XEROX CO., LTD. (JP) 1992-05-05 US disclosed
EP-0446030-A2 Solventless silicone release coating MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-09-11 EP disclosed
US-4965160-A CHARGE QUALITY FUJI XEROX CO., LTD. (JP) 1990-10-23 US disclosed
US-4954409-A FLUORINATED ACRYLIC POLYMER FUJI XEROX CO., LTD. (JP) 1990-09-04 US disclosed
US-4868083-A Developer carrier and process for producing the same FUJI XEROX CO., LTD. (JP) 1989-09-19 US disclosed
EP-0140530-B1 LATENTLY-CURABLE ORGANOSILICONE RELEASE COATING COMPOSITION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-03-08 EP disclosed
US-4791041-A FLUORINATED ALKYL (METH)ARYLATE COPOLYMER OVERCOATINGS; ANTISOILANTS; ANTISTICKING AGENTS FUJI XEROX CO., LTD. (JP) 1988-12-13 US disclosed
US-4533575-A ETHYLENICALLY UNSATURATED POLYSILOXANE AND POLYHYDROSILOXANE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-08-06 US disclosed
EP-0140530-A1 Latently-curable organosilicone release coating composition MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-05-08 EP disclosed
US-4504645-A GELATION INHIBITION USING A MONOESTER OR -AMIDE OF AN UNSATURATED DICARBOXYLIC ACID; SHELF LIFE; HEAT CURING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-03-12 US disclosed