SCHEMBL147573

SCHEMBL147573

[CH2]C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.36
CA2 P00918 2/20 0.33
CA1 P00915 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6655835 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL503984 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL954243 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL1828060 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL958058 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL216042 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL5491848 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL445081 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL5492172 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL143822 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 651 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2532663-B1 Naphthalenetetracarboxylic acid derivatives and their use as semiconductors BASF SE (DE) 2016-03-16 EP claimed
EP-2181172-B1 HALOGEN-CONTAINING PERYLENETETRACARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF BASF SE (DE) 2016-02-24 EP claimed
US-9243089-B2 Copolymer-modified nanoparticles, especially for use in medical articles BARCIKOWSKI STEPHAN (DE) 2016-01-26 US claimed
US-20140155603-A1 HALOGEN-CONTAINING PERYLENETETRACARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF BASF SE (DE) 2014-06-05 US claimed
US-8674104-B2 Halogen-containing perylenetetracarboxylic acid derivatives and the use thereof BASF SE (DE) 2014-03-18 US claimed
US-20130123495-A1 HALOGEN-CONTAINING PERYLENETETRACARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF CLAP CO., LTD. (KR) 2013-05-16 US claimed
EP-2532663-A1 Naphthalenecarboxylic acid derivatives and their use as semiconductors BASF SE (DE) 2012-12-12 EP claimed
US-20090191135-A1 METHODS FOR THE DISPERSION OF WATER-SOLUABLE OR HYDROPHILIC SUBSTANCES IN A SUPERCRITICALLY PRESSURIZED FLUID ETHYPHARM CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS 2009-07-30 US claimed
US-7419620-B2 Dichroic mixtures ROLIC LTD C/O ROLIC TECHNOLOGIES LTD (CH) 2008-09-02 US claimed
EP-1385914-B1 DICHROIC MIXTURE ROLIC AG (CH) 2008-07-23 EP claimed
EP-1617814-B1 METHOD FOR THE DISPERSION OF WATER-SOLUBLE OR HYDROPHILIC SUBSTANCES IN A SUPERCRITICALLY PRESSURIZED FLUID ETHYPHARM SA (FR) 2008-05-28 EP claimed
EP-1256602-A1 Dichroic mixture Rolic AG (CH) 2002-11-13 EP claimed
US-6252245-B1 THIN FILM TRANSISTORS WITH DIIMIDE GROUPS BELL NORTHERN RESEARCH, LLC 2001-06-26 US claimed
EP-1041653-A2 Device comprising organic N-channel semiconductor material LUCENT TECHNOLOGIES INC. (US) 2000-10-04 EP claimed
WO-1999033790-A1 INSECTICIDAL FLUORO-SUBSTITUTED BENZOYLUREAS NIHON BAYER AGROCHEM K.K. (DE) 1999-07-08 WO claimed
US-4945139-A SOLVENT RESISTANCE, POLYPHOSPHAZINES ETHYL CORPORATION (US) 1990-07-31 US claimed
EP-0003663-A2 Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them AMERICAN CYANAMID COMPANY (US) 1979-08-22 EP claimed
US-3996226-A METHOLATED MELAMINES NOBEL HOECHST CHIMIE (FR) 1976-12-07 US claimed
WO-2024135958-A1 LAMINATED FILM FOR SOLAR MODULE HAVING EXCELLENT RADIATION COOLING PROPERTIES, AND SOLAR MODULE COMPRISING SAME 이근수 2024-06-27 WO disclosed
US-3996226-A METHOLATED MELAMINES NOBEL HOECHST CHIMIE (FR) 1976-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090191135-A1 METHODS FOR THE DISPERSION OF WATER-SOLUABLE OR HYDROPHILIC SUBSTANCES IN A SUPERCRITICALLY PRESSURIZED FLUID AQP1, AQP3, AQP4 LMNA 2636/4885THRB 3246/4885CA2 102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.