Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 7/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14384114 | 1.00 | L3MBTL1 (0.44) | L3MBTL1CTSKKAT6ACTSBCTSS | |
| SCHEMBL5631694 | 0.84 | L3MBTL1 (0.50) | L3MBTL1CTSKKAT6ACTSBCTSS | |
| SCHEMBL5631689 | 0.84 | L3MBTL1 (0.50) | L3MBTL1CTSKKAT6ACTSBCTSS | |
| SCHEMBL14384120 | 0.84 | CTSK (0.44) | L3MBTL1CTSKKAT6ACTSBCTSS | |
| SCHEMBL14384118 | 0.84 | CTSK (0.44) | L3MBTL1CTSKKAT6ACTSBCTSS | |
| SCHEMBL5632090 | 0.82 | L3MBTL1 (0.43) | L3MBTL1CTSKKAT6ACTSBCTSS | |
| SCHEMBL6618230 | 0.80 | CTSK (0.47) | CTSKCTSBCTSS | |
| SCHEMBL15124929 | 0.77 | ALOX5AP (0.49) | L3MBTL1KAT6ACA12CA1CA7 | |
| SCHEMBL6635507 | 0.76 | CTSK (0.46) | CTSKCTSBCTSS | |
| SCHEMBL7467714 | 0.76 | CTSK (0.46) | CTSKCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7288541-B2 | Propylcarbamate derivatives as inhibitors of serine and cysteine proteases | SMITHKLINE BEECHAM CORPORATION (US) | 2007-10-30 | — | — | US | disclosed |
| US-7288541-B2 | Propylcarbamate derivatives as inhibitors of serine and cysteine proteases | SMITHKLINE BEECHAM CORPORATION (US) | 2007-10-30 | — | — | US | disclosed |