Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 2/20 | 0.38 |
| ▸ | EED | O75530 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3387608 | 0.86 | KDM1A (0.43) | KMT2AHTR6KDM1AEEDCHRNB2 | |
| SCHEMBL334939 | 0.84 | ACHE (0.44) | KMT2ASTAT3CYP1A2CYP2D6CA12 | |
| SCHEMBL336340 | 0.84 | ALDH1A1 (0.44) | KMT2ASTAT3CYP1A2CYP2D6CA12 | |
| SCHEMBL13068833 | 0.83 | HTR6 (0.48) | KMT2AHTR6KDM1ASTAT3CYP1A2 | |
| SCHEMBL7026133 | 0.83 | ALDH1A1 (0.46) | KMT2ACYP1A2CYP2D6KCNH2CA12 | |
| SCHEMBL25642110 | 0.82 | HTR6 (0.43) | HTR6STAT3CYP1A2CYP2D6CA12 | |
| SCHEMBL244134 | 0.81 | CYP2D6 (0.43) | KMT2ASTAT3CYP1A2CYP2D6CA12 | |
| SCHEMBL8790104 | 0.78 | HTR6 (0.45) | HTR6KDM1ACHRNB2CHRNA4STAT3 | |
| SCHEMBL16797263 | 0.78 | HTR6 (0.45) | HTR6KDM1ACHRNB2CHRNA4STAT3 | |
| SCHEMBL8790095 | 0.78 | HTR6 (0.45) | HTR6KDM1ACHRNB2CHRNA4STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007134298-A2 | THERAPEUTIC COMPOUNDS AND THEIR USE IN CANCER | MYRIAD GENETICS, INC. (US) | 2007-11-22 | — | — | WO | disclosed |