Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 6/20 | 0.38 |
| ▸ | PIM1 | P11309 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14385643 | 0.94 | ALDH1A1 (0.38) | SQORPIM1ALDH1A1MAPTPOLB | |
| SCHEMBL14385662 | 0.89 | SQOR (0.37) | SQORPIM1ALDH1A1MAPTPOLB | |
| SCHEMBL14385272 | 0.89 | SQOR (0.37) | SQORPIM1ALDH1A1MAPTPOLB | |
| SCHEMBL14385642 | 0.88 | ALDH1A1 (0.37) | PIM1ALDH1A1MAPTPOLBLMNA | |
| SCHEMBL14385603 | 0.86 | MEN1 (0.35) | ALDH1A1POLBKDM4ENPC1KMT2A | |
| SCHEMBL14385810 | 0.84 | NPSR1 (0.34) | SQORPIM1ALDH1A1MAPTPOLB | |
| SCHEMBL14385873 | 0.79 | PIM1 (0.40) | SQORPIM1ALDH1A1MAPTPOLB | |
| SCHEMBL14385814 | 0.79 | KMT2A (0.34) | ALDH1A1MAPTPOLBLMNAKDM4E | |
| SCHEMBL14385583 | 0.77 | CACNA1D (0.31) | — | |
| SCHEMBL14392507 | 0.76 | SQOR (0.34) | SQORALDH1A1MAPTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007124545-A1 | INTEGRASE INHIBITORS - 2 | AVEXA LIMITED (AU) | 2007-11-08 | — | — | WO | disclosed |