Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SQOR | Q9Y6N5 | 5/20 | 0.36 |
| ▸ | PIM1 | P11309 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14385243 | 0.94 | SQOR (0.38) | ALDH1A1NPSR1LMNASMN1; SMN2KDM4E | |
| SCHEMBL14385810 | 0.90 | NPSR1 (0.34) | ALDH1A1NPSR1LMNASMN1; SMN2KDM4E | |
| SCHEMBL14385642 | 0.85 | ALDH1A1 (0.37) | ALDH1A1NPSR1LMNASMN1; SMN2KDM4E | |
| SCHEMBL14385272 | 0.83 | SQOR (0.37) | ALDH1A1NPSR1KDM4EKMT2APPARG | |
| SCHEMBL14385662 | 0.83 | SQOR (0.37) | ALDH1A1NPSR1KDM4EKMT2APPARG | |
| SCHEMBL14385603 | 0.81 | MEN1 (0.35) | ALDH1A1KDM4EKMT2APPARGNPC1 | |
| SCHEMBL14385814 | 0.75 | KMT2A (0.34) | ALDH1A1NPSR1LMNASMN1; SMN2KDM4E | |
| SCHEMBL14385873 | 0.74 | PIM1 (0.40) | ALDH1A1NPSR1LMNAKMT2AMAPT | |
| SCHEMBL14385641 | 0.74 | KDM4E (0.39) | ALDH1A1NPSR1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL14385583 | 0.72 | CACNA1D (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007124545-A1 | INTEGRASE INHIBITORS - 2 | AVEXA LIMITED (AU) | 2007-11-08 | — | — | WO | disclosed |