Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13409985 | 0.89 | L3MBTL1 (0.51) | ALDH1A1KMT2AMEN1TSHRL3MBTL1 | |
| SCHEMBL13409046 | 0.87 | ALDH1A1 (0.48) | KDM4EALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL13409986 | 0.87 | CYP3A4 (0.46) | KDM4EKMT2AMEN1TSHR | |
| SCHEMBL13409979 | 0.87 | KMT2A (0.55) | KDM4EALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL13409679 | 0.86 | PRKAA2 (0.49) | KDM4EALDH1A1KMT2AMEN1CYP2D6 | |
| SCHEMBL13409748 | 0.86 | CYP3A4 (0.46) | KMT2AMEN1TSHRCYP2D6 | |
| SCHEMBL13409111 | 0.85 | KMT2A (0.51) | ALDH1A1KMT2AMEN1TSHRCA12 | |
| SCHEMBL13409686 | 0.84 | PRKAB2 (0.45) | KMT2AMEN1TSHRACKR3POLB | |
| SCHEMBL14078600 | 0.84 | KDM4E (0.45) | KDM4EALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL13392202 | 0.84 | KDM4E (0.45) | KDM4EALDH1A1KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300941-B2 | Non-imidazole compounds | SCHERING CORPORATION (US) | 2007-11-27 | — | — | US | disclosed |