Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | UBE2I | P63279 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14391015 | 0.90 | MEN1 (0.38) | PTGS1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL3594349 | 0.87 | KDM4E (0.49) | PTGS1CYP3A4KCNH2MEN1KMT2A | |
| SCHEMBL14390891 | 0.83 | PTGS1 (0.44) | PTGS1CYP3A4KCNH2MEN1KMT2A | |
| SCHEMBL14390694 | 0.82 | IKBKB (0.39) | PTGS1CYP3A4MEN1KMT2AMAPT | |
| SCHEMBL14390890 | 0.82 | PTGS1 (0.45) | PTGS1CYP3A4KCNH2MEN1KMT2A | |
| SCHEMBL14390692 | 0.82 | PTGS1 (0.43) | PTGS1CYP3A4KCNH2MEN1KMT2A | |
| SCHEMBL3590027 | 0.78 | KDM4E (0.49) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL3594101 | 0.77 | MEN1 (0.45) | PTGS1CYP3A4KCNH2MEN1KMT2A | |
| SCHEMBL14391020 | 0.74 | IKBKB (0.45) | PTGS1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL14391012 | 0.73 | CHEK2 (0.41) | PTGS1MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007124546-A1 | INTEGRASE INHIBITORS 3 | AVEXA LIMITED (AU) | 2007-11-08 | — | — | WO | disclosed |