Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14391013 | 0.91 | KDM4E (0.41) | ALDH1A1HPGDKDM4EGLAHSD17B10 | |
| SCHEMBL3593738 | 0.89 | HPGD (0.45) | ALDH1A1HPGDKDM4EGLAHSD17B10 | |
| SCHEMBL3595419 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EGLAHSD17B10 | |
| SCHEMBL14390890 | 0.79 | PTGS1 (0.45) | ALDH1A1HPGDKDM4EHSD17B10GAA | |
| SCHEMBL14390908 | 0.77 | HPGDS (0.39) | ALDH1A1HPGDKDM4EHSD17B10GAA | |
| SCHEMBL3582806 | 0.75 | TSHR (0.43) | ALDH1A1HPGDKDM4EGLAHSD17B10 | |
| SCHEMBL14390907 | 0.74 | KMT2A (0.46) | ALDH1A1HPGDKDM4EGLAHSD17B10 | |
| SCHEMBL14390864 | 0.72 | MAPT (0.38) | ALDH1A1HPGDKDM4EMAPTRAB9A | |
| SCHEMBL3594101 | 0.72 | MEN1 (0.45) | ALDH1A1GAAMAPTRAB9ANPC1 | |
| SCHEMBL14390695 | 0.72 | CSNK2A1 (0.43) | KDM4EGAAMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007124546-A1 | INTEGRASE INHIBITORS 3 | AVEXA LIMITED (AU) | 2007-11-08 | — | — | WO | disclosed |