Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | PDE1A | P54750 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3594942 | 0.87 | PDE5A (0.46) | HPGDSKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL14390695 | 0.83 | CSNK2A1 (0.43) | HPGDSKMT2AMAPTKDM4ENPSR1 | |
| SCHEMBL14391013 | 0.83 | KDM4E (0.41) | HPGDSKMT2AALDH1A1KDM4ETNFRSF1A | |
| SCHEMBL14390899 | 0.80 | ADORA2A (0.46) | HPGDSKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL14390903 | 0.80 | SMN1; SMN2 (0.47) | HPGDSKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL3582806 | 0.79 | TSHR (0.43) | KMT2AALDH1A1MAPTKDM4ENPSR1 | |
| SCHEMBL14385615 | 0.78 | HPGD (0.39) | KMT2AALDH1A1MAPTKDM4ENPSR1 | |
| SCHEMBL14390862 | 0.77 | ALDH1A1 (0.39) | ALDH1A1MAPTKDM4ETNFRSF1AGAA | |
| SCHEMBL3584180 | 0.76 | HPGDS (0.44) | HPGDSKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL3592534 | 0.76 | POLB (0.43) | HPGDSKMT2AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007124546-A1 | INTEGRASE INHIBITORS 3 | AVEXA LIMITED (AU) | 2007-11-08 | — | — | WO | disclosed |