Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.46 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.46 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1338456 | 0.83 | L3MBTL1 (0.61) | KDM4EHSD17B10MAPTHIF1AALDH1A1 | |
| SCHEMBL1019293 | 0.81 | HPGD (0.49) | KDM4EHSD17B10MAPTHIF1AALDH1A1 | |
| SCHEMBL12956408 | 0.81 | L3MBTL1 (0.58) | KDM4EHSD17B10MAPTHIF1AALDH1A1 | |
| SCHEMBL19903081 | 0.79 | KDM4E (0.46) | KDM4EHSD17B10MAPTHIF1AALDH1A1 | |
| SCHEMBL12391731 | 0.77 | POLB (0.51) | KDM4EHSD17B10MAPTHIF1AALDH1A1 | |
| SCHEMBL10868710 | 0.75 | ALDH1A1 (0.58) | PARP1ALDH1A1 | |
| SCHEMBL3753741 | 0.74 | POLB (0.47) | KDM4EHSD17B10MAPTHIF1AALDH1A1 | |
| SCHEMBL25108756 | 0.73 | RAB9A (0.45) | KDM4EHSD17B10MAPTHIF1AALDH1A1 | |
| SCHEMBL2606619 | 0.72 | PARP1 (0.62) | KDM4EHSD17B10MAPTPARP1ALDH1A1 | |
| SCHEMBL818929 | 0.72 | ALDH1A1 (0.70) | MAPTPARP1ALDH1A1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007121920-A2 | PURINE DERIVATIVES FOR USE AS ADENOSIN A2A RECEPTOR AGONISTS | NOVARTIS AG (CH) | 2007-11-01 | — | — | WO | disclosed |