Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4995737 | 0.82 | MAPK1 (0.50) | KDM4EL3MBTL1PTGER4MAPK1TSHR | |
| SCHEMBL4701058 | 0.81 | KDM4E (0.56) | KDM4EL3MBTL1PDE4DPTGER4ALDH1A1 | |
| SCHEMBL14918993 | 0.80 | KDM4E (0.71) | KDM4EL3MBTL1MAPK1MRGPRX4ALDH1A1 | |
| SCHEMBL18552419 | 0.78 | KDM4E (0.44) | KDM4EL3MBTL1PDE4DGPR35PTGER4 | |
| SCHEMBL561626 | 0.78 | GPR35 (0.47) | KDM4EL3MBTL1PDE4DGPR35MAPK1 | |
| SCHEMBL7226331 | 0.76 | KDM4E (0.47) | KDM4EL3MBTL1PDE4DPTGER4MAPK1 | |
| SCHEMBL23714070 | 0.75 | CYP1A2 (0.47) | KDM4EL3MBTL1PTGER4MRGPRX4ALDH1A1 | |
| SCHEMBL16228012 | 0.75 | KDM4E (0.46) | KDM4EL3MBTL1PTGER4MAPK1MRGPRX4 | |
| SCHEMBL187887 | 0.75 | KDM4E (0.46) | KDM4EL3MBTL1MAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7236303 | 0.75 | CTSA (0.48) | KDM4EL3MBTL1PDE4DMAPK1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654261-B1 | HEPATITIS C INHIBITOR COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2007-11-14 | — | — | EP | disclosed |