Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 2/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GALR2 | O43603 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8443380 | 0.84 | MAPT (0.54) | ALDH1A1PKML3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL15498664 | 0.83 | ALDH1A1 (0.50) | ALDH1A1PKML3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL3527609 | 0.83 | ALDH1A1 (0.50) | ALDH1A1PKML3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL12466651 | 0.83 | MAPT (0.53) | ALDH1A1PKML3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL4819821 | 0.82 | KMT2A (0.50) | ALDH1A1PKMMAPTSMN1; SMN2KMT2A | |
| SCHEMBL3833396 | 0.82 | MAPT (0.54) | ALDH1A1PKMMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL29856467 | 0.80 | KMT2A (0.48) | ALDH1A1PKMMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL16412559 | 0.80 | ALDH1A1 (0.47) | ALDH1A1PKML3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL6072863 | 0.80 | HPD (0.50) | ALDH1A1PKML3MBTL1MAPTMAPK1 | |
| SCHEMBL10091749 | 0.80 | ALDH1A1 (0.77) | ALDH1A1PKML3MBTL1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183232-B1 | MONOFLUOROALKYL DERIVATIVES | LILLY CO ELI (US) | 2007-10-03 | — | — | EP | disclosed |