Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4819821 | 0.90 | KMT2A (0.50) | KMT2AALDH1A1POLBKDM4EPKM | |
| SCHEMBL3582306 | 0.82 | MAPT (0.52) | KMT2AALDH1A1POLBKDM4EPKM | |
| SCHEMBL8491427 | 0.82 | VCAM1 (0.53) | KMT2AALDH1A1POLBPKMSMN1; SMN2 | |
| SCHEMBL1304636 | 0.82 | KMT2A (0.60) | KMT2AALDH1A1POLBKDM4EPKM | |
| SCHEMBL8443380 | 0.81 | MAPT (0.54) | KMT2AALDH1A1KDM4EPKMSMN1; SMN2 | |
| SCHEMBL12466651 | 0.80 | MAPT (0.53) | KMT2AALDH1A1PKMSMN1; SMN2MAPT | |
| SCHEMBL15498664 | 0.80 | ALDH1A1 (0.50) | KMT2AALDH1A1POLBKDM4EPKM | |
| SCHEMBL14394686 | 0.80 | ALDH1A1 (0.50) | KMT2AALDH1A1POLBKDM4EPKM | |
| SCHEMBL3527609 | 0.80 | ALDH1A1 (0.50) | KMT2AALDH1A1POLBKDM4EPKM | |
| SCHEMBL3575526 | 0.80 | GAA (0.47) | KMT2AALDH1A1POLBPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12435059-B2 | AMP-activated protein kinase inhibitors and methods of making and using the same | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2025-10-07 | — | — | US | disclosed |
| US-20220289707-A1 | AMP-ACTIVATED PROTEIN KINASE INHIBITORS AND METHODS OF MAKING AND USING THE SAME | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2022-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12435059-B2 | AMP-activated protein kinase inhibitors and methods of making and using the same | PRKAA1, PRKAA2, PRKAG1 | KMT2A 3285/4885ALDH1A1 849/4885POLB 2054/4885 |
| US-20220289707-A1 | AMP-ACTIVATED PROTEIN KINASE INHIBITORS AND METHODS OF MAKING AND USING THE SAME | PRKAA1, PRKAA2, PRKAG1 | KMT2A 3285/4885ALDH1A1 849/4885POLB 2054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.