Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7193200 | 0.80 | MAPT (0.43) | NPC1LMNACRBNMAOAMAOB | |
| SCHEMBL14584671 | 0.78 | NPC1 (0.47) | NPC1LMNACRBNMAOAMAOB | |
| SCHEMBL1443189 | 0.77 | MAPT (0.53) | NPC1LMNACRBNMAOAMAOB | |
| SCHEMBL1443188 | 0.77 | MAPT (0.53) | NPC1LMNACRBNMAOAMAOB | |
| SCHEMBL21556950 | 0.75 | MAOA (0.49) | NPC1LMNACRBNMAOAMAOB | |
| SCHEMBL5207455 | 0.75 | MAOB (0.56) | LMNAMAOAMAOBMAPTPOLB | |
| SCHEMBL6765500 | 0.74 | NPC1 (0.56) | NPC1LMNACRBNMAOAMAOB | |
| SCHEMBL11588202 | 0.74 | NPC1 (0.55) | NPC1LMNACRBNMAOAMAOB | |
| SCHEMBL29410461 | 0.74 | ALDH1A1 (0.61) | NPC1LMNACRBNMAOAMAOB | |
| SCHEMBL7193198 | 0.73 | TSHR (0.36) | NPC1LMNACRBNMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362855-B1 | BETA-LACTAM COMPOUNDS, PROCESS FOR REPODUCING THE SAME AND SERUM CHOLESTEROL-LOWERING AGENTS CONTAINING THE SAME | KOTOBUKI PHARMACEUTICAL CO LTD (JP) | 2007-10-03 | — | — | EP | disclosed |