Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19361310 | 0.94 | ALDH1A1 (0.51) | MAOAMAOBLMNANPC1CRBN | |
| SCHEMBL19361311 | 0.88 | MAOA (0.47) | MAOAMAOBNPC1ALDH1A1MAPT | |
| SCHEMBL16216281 | 0.85 | APP (0.36) | MAOAMAOBLMNAALDH1A1MAPT | |
| SCHEMBL20852480 | 0.85 | MAPT (0.35) | MAOAMAOBLMNANPC1CRBN | |
| SCHEMBL10305087 | 0.85 | APP (0.36) | MAOAMAOBLMNAALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL3118484 | 0.84 | KCNH2 (0.36) | MAOAMAOBLMNAALDH1A1MAPT | |
| SCHEMBL29410461 | 0.78 | ALDH1A1 (0.61) | MAOAMAOBLMNANPC1CRBN | |
| SCHEMBL14395035 | 0.75 | NPC1 (0.64) | MAOAMAOBLMNANPC1CRBN | |
| SCHEMBL19361357 | 0.72 | PDE4A (0.41) | MAOAMAOBLMNANPC1ALDH1A1 | |
| SCHEMBL18746539 | 0.70 | NPC1 (0.47) | MAOAMAOBLMNANPC1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567029-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2019-11-13 | — | — | EP | disclosed |