Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.45 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | EEF2K | O00418 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | NAT1 | P18440 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1005116 | 0.91 | ERN1 (0.52) | ERN1TTRPTGS2NAT1APP | |
| SCHEMBL143965 | 0.86 | CYP2C9 (0.56) | ERN1SRCCYP2C9CYP1A2CYP3A4 | |
| SCHEMBL7962088 | 0.80 | XDH (0.50) | ERN1TTRPTGS2NAT1APP | |
| SCHEMBL29459683 | 0.80 | EGFR (0.53) | ERN1SRCCYP2C9CYP1A2CYP3A4 | |
| SCHEMBL299751 | 0.80 | EGFR (0.53) | ERN1SRCCYP2C9CYP1A2CYP3A4 | |
| SCHEMBL5646596 | 0.78 | ERN1 (0.56) | ERN1SRCCYP2C9CYP1A2CYP3A4 | |
| SCHEMBL22991663 | 0.78 | TTR (0.42) | SRCCYP2C9CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL26856769 | 0.77 | KDM4E (0.43) | ERN1SRCCYP2C9CYP1A2CYP3A4 | |
| SCHEMBL31554021 | 0.77 | KDM4E (0.43) | ERN1SRCCYP2C9CYP1A2CYP3A4 | |
| SCHEMBL24981909 | 0.77 | ERN1 (0.44) | ERN1TTRPTGS2ALOX5NAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107759588-B | Phenyl- (pyrazolo [1,5-a ] pyridine-3-yl) ketone derivative | 江苏新元素医药科技有限公司 | 2020-10-23 | — | — | CN | claimed |
| WO-2024135708-A1 | METHOD FOR PRODUCING COMPOUND, POLYMER, COMPOSITION, AND PATTERN FORMATION METHOD | 三菱瓦斯化学株式会社 | 2024-06-27 | — | — | WO | disclosed |
| US-20230286890-A1 | METHOD FOR SYNTHESIZING 3,5-DIIODO-4-HYDROXY BENZYL ALCOHOL | DIVERCHIM CDMO (FR) | 2023-09-14 | — | — | US | disclosed |
| US-20230286890-A1 | METHOD FOR SYNTHESIZING 3,5-DIIODO-4-HYDROXY BENZYL ALCOHOL | DIVERCHIM CDMO (FR) | 2023-09-14 | — | — | US | disclosed |
| CN-107759588-B | Phenyl- (pyrazolo [1,5-a ] pyridine-3-yl) ketone derivative | 江苏新元素医药科技有限公司 | 2020-10-23 | — | — | CN | disclosed |
| CN-106065010-B | For treating or preventing the compound of hyperuricemia or gout | 镇江新元素医药科技有限公司 | 2019-01-01 | — | — | CN | disclosed |
| US-6683107-B2 | THERAPY OF METABOLISM DISORDERS | WYETH | 2004-01-27 | — | — | US | disclosed |
| US-20030073709-A1 | Furans, benzofurans, and thiophenes useful in the treatment of insulin resistance and hyperglycemia | WYETH | 2003-04-17 | — | — | US | disclosed |
| US-6451845-B1 | ANTIDIABETIC AGENTS | WYETH | 2002-09-17 | — | — | US | disclosed |
| US-20020035272-A1 | Furans, benzofurans, and thiophenes useful in the treatment of insulin resistance and hyperglycemia | AMERICAN HOME PRODUCTS CORPORATION | 2002-03-21 | — | — | US | disclosed |
| US-6248764-B1 | ANTIDIABETIC AGENT; HYPOGLYCEMIC AGENT | AMERICAN HOME PRODUCTS CORPORATION | 2001-06-19 | — | — | US | disclosed |
| US-6103708-A | USEFUL IN TREATING METABOLIC DISORDERS RELATED TO INSULIN RESISTANCE OR HYPERGLYCEMIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073709-A1 | Furans, benzofurans, and thiophenes useful in the treatment of insulin resistance and hyperglycemia | GPR119, INSR, FFAR3 | ERN1 2738/4885SRC 2498/4885CYP2C9 1450/4885 |
| US-20020035272-A1 | Furans, benzofurans, and thiophenes useful in the treatment of insulin resistance and hyperglycemia | INSR, GPR119, FFAR3 | ERN1 2603/4885SRC 2920/4885CYP2C9 1418/4885 |
| US-20230286890-A1 | METHOD FOR SYNTHESIZING 3,5-DIIODO-4-HYDROXY BENZYL ALCOHOL | ADH1C, ADH5, ADH1A | ERN1 2879/4885SRC 3224/4885CYP2C9 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.