⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994436 | 0.73 | CES1 (0.37) | — | |
| SCHEMBL13093737 | 0.71 | — | — | |
| SCHEMBL9292897 | 0.71 | — | — | |
| Propionic Acid SCHEMBL27990618 | 0.67 | FFAR3 (0.50) | — | |
| SCHEMBL1291088 | 0.67 | — | — | |
| SCHEMBL1667271 | 0.67 | — | — | |
| SCHEMBL10243245 | 0.67 | — | — | |
| SCHEMBL11339178 | 0.67 | — | — | |
| SCHEMBL9775079 | 0.66 | ALDH1A1 (0.35) | — | |
| SCHEMBL9775075 | 0.66 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102482298-B | (E) -styryl-alkynyl substituted silicon compounds and method for obtaining (E) -styryl-alkynyl substituted silicon compounds | UNIV ADAM MICKIEWICZ | 2015-03-11 | — | — | CN | claimed |
| US-8680310-B2 | (E)-styryl-alkynylsubstituted silicon compounds and method of obtaining (E)-styryl-alkynylsubstituted silicon compounds | ADAM MICKIEWICZ UNIVERSITY (PL) | 2014-03-25 | — | — | US | claimed |
| EP-2475670-A1 | NEW (E)-STYRYL-ALKYNYLSUBSTITUTED SILICON COMPOUNDS AND METHOD OF OBTAINING (E)- STYRYL-ALKYNYLSUBSTITUTED SILICON COMPOUNDS | Adam Mickiewicz University (PL) | 2012-07-18 | — | — | EP | claimed |
| US-20120178955-A1 | NEW (E)-STYRYL-ALKYNYLSUBSTITUTED SILICON COMPOUNDS AND METHOD OF OBTAINING (E)-STYRYL-ALKYNYLSUBSTITUTED SILICON COMPOUNDS | ADAM MICKIEWICZ UNIVERSITY (PL) | 2012-07-12 | — | — | US | claimed |
| CN-102482298-A | Novel -styryl-alkynyl substituted silicon compounds and method for obtaining -styryl-alkynyl substituted silicon compounds | UNIV ADAM MICKIEWICZ | 2012-05-30 | — | — | CN | claimed |
| WO-2011031171-A1 | NEW (E)-STYRYL-ALKYNYLSUBSTITUTED SILICON COMPOUNDS AND METHOD OF OBTAINING (E)- STYRYL-ALKYNYLSUBSTITUTED SILICON COMPOUNDS | ADAM MICKIEWICZ UNIVERSITY (PL) | 2011-03-17 | — | — | WO | claimed |
| CN-102482298-B | (E) -styryl-alkynyl substituted silicon compounds and method for obtaining (E) -styryl-alkynyl substituted silicon compounds | UNIV ADAM MICKIEWICZ | 2015-03-11 | — | — | CN | disclosed |
| CN-102482298-B | (E) -styryl-alkynyl substituted silicon compounds and method for obtaining (E) -styryl-alkynyl substituted silicon compounds | UNIV ADAM MICKIEWICZ | 2015-03-11 | — | — | CN | disclosed |
| US-8680310-B2 | (E)-styryl-alkynylsubstituted silicon compounds and method of obtaining (E)-styryl-alkynylsubstituted silicon compounds | ADAM MICKIEWICZ UNIVERSITY (PL) | 2014-03-25 | — | — | US | disclosed |
| US-8680310-B2 | (E)-styryl-alkynylsubstituted silicon compounds and method of obtaining (E)-styryl-alkynylsubstituted silicon compounds | ADAM MICKIEWICZ UNIVERSITY (PL) | 2014-03-25 | — | — | US | disclosed |
| EP-2475670-A1 | NEW (E)-STYRYL-ALKYNYLSUBSTITUTED SILICON COMPOUNDS AND METHOD OF OBTAINING (E)- STYRYL-ALKYNYLSUBSTITUTED SILICON COMPOUNDS | Adam Mickiewicz University (PL) | 2012-07-18 | — | — | EP | disclosed |
| EP-2475670-A1 | NEW (E)-STYRYL-ALKYNYLSUBSTITUTED SILICON COMPOUNDS AND METHOD OF OBTAINING (E)- STYRYL-ALKYNYLSUBSTITUTED SILICON COMPOUNDS | Adam Mickiewicz University (PL) | 2012-07-18 | — | — | EP | disclosed |
| US-20120178955-A1 | NEW (E)-STYRYL-ALKYNYLSUBSTITUTED SILICON COMPOUNDS AND METHOD OF OBTAINING (E)-STYRYL-ALKYNYLSUBSTITUTED SILICON COMPOUNDS | ADAM MICKIEWICZ UNIVERSITY (PL) | 2012-07-12 | — | — | US | disclosed |
| US-20120178955-A1 | NEW (E)-STYRYL-ALKYNYLSUBSTITUTED SILICON COMPOUNDS AND METHOD OF OBTAINING (E)-STYRYL-ALKYNYLSUBSTITUTED SILICON COMPOUNDS | ADAM MICKIEWICZ UNIVERSITY (PL) | 2012-07-12 | — | — | US | disclosed |
| CN-102482298-A | Novel -styryl-alkynyl substituted silicon compounds and method for obtaining -styryl-alkynyl substituted silicon compounds | UNIV ADAM MICKIEWICZ | 2012-05-30 | — | — | CN | disclosed |
| CN-102482298-A | Novel -styryl-alkynyl substituted silicon compounds and method for obtaining -styryl-alkynyl substituted silicon compounds | UNIV ADAM MICKIEWICZ | 2012-05-30 | — | — | CN | disclosed |
| WO-2011031171-A1 | NEW (E)-STYRYL-ALKYNYLSUBSTITUTED SILICON COMPOUNDS AND METHOD OF OBTAINING (E)- STYRYL-ALKYNYLSUBSTITUTED SILICON COMPOUNDS | ADAM MICKIEWICZ UNIVERSITY (PL) | 2011-03-17 | — | — | WO | disclosed |
| WO-2011031171-A1 | NEW (E)-STYRYL-ALKYNYLSUBSTITUTED SILICON COMPOUNDS AND METHOD OF OBTAINING (E)- STYRYL-ALKYNYLSUBSTITUTED SILICON COMPOUNDS | ADAM MICKIEWICZ UNIVERSITY (PL) | 2011-03-17 | — | — | WO | disclosed |