⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3148457 | 0.70 | ALDH1A1 (0.31) | — | |
| SCHEMBL1439684 | 0.67 | — | — | |
| SCHEMBL18586595 | 0.65 | — | — | |
| SCHEMBL10243245 | 0.65 | — | — | |
| SCHEMBL1291088 | 0.65 | — | — | |
| SCHEMBL11339178 | 0.65 | — | — | |
| SCHEMBL9520232 | 0.63 | — | — | |
| SCHEMBL3897151 | 0.63 | — | — | |
| SCHEMBL3897156 | 0.63 | — | — | |
| SCHEMBL13093737 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105579480-A | Method for making UV absorbing ophthalmic lenses | NOVARTIS AG | 2016-05-11 | — | — | CN | claimed |
| CN-103380153-B | Amphiphilic polysiloxane prepolymers and their use | NOVARTIS AG (CH) | 2015-12-02 | — | — | CN | claimed |
| CN-103298602-B | Manufacture the method for silicone hydrogel contact lens | NOVARTIS AG (CH) | 2015-09-23 | — | — | CN | claimed |
| CN-104169334-A | Organopolysiloxanes including silicon-bonded trialkylsilyl-substituted organic groups | DOW CORNING | 2014-11-26 | — | — | CN | claimed |
| CN-102115515-B | Copolymer for improving wettability of silicone hydrogel, silicone hydrogel composition containing same and ophthalmic article prepared therefrom | FAR EASTERN NEW CENTURY CORP | 2014-06-18 | — | — | CN | claimed |
| CN-103380153-A | Amphiphilic polysiloxane prepolymers and their use | NOVARTIS AG | 2013-10-30 | — | — | CN | claimed |
| CN-102639636-A | Method for increasing ion transmission rate of contact lens | NOVARTIS AG | 2012-08-15 | — | — | CN | claimed |
| CN-102464744-A | Chlorinated polymers that enhance wettability of silicone hydrogels, silicone hydrogels comprising the same, and ophthalmic articles made therefrom | FAR EASTERN NEW CENTURY CORP | 2012-05-23 | — | — | CN | claimed |
| CN-102115515-A | Copolymer for improving wettability of silicone hydrogel, silicone hydrogel composition containing same and ophthalmic article prepared therefrom | FAR EASTERN NEW CENTURY CORP | 2011-07-06 | — | — | CN | claimed |
| CN-101883799-A | High water content silicone hydrogels | BAUSCH & LOMB | 2010-11-10 | — | — | CN | claimed |
| CN-1675252-B | Macromer combination and preparation method thereof | JOHNSON & JOHNSON VISION CARE | 2010-05-12 | — | — | CN | claimed |
| CN-114051497-B | Chromene compounds and photochromic optical articles | 株式会社德山 | 2024-06-28 | — | — | CN | disclosed |
| EP-3936091-B1 | METHOD FOR ABSORBING OR DISCHARGING WATER IN OPHTHALMIC MEDICAL DEVICE AND OPHTHALMIC MEDICAL DEVICE | UNIV TOHOKU (JP) | 2023-07-19 | — | — | EP | disclosed |
| CN-115997158-A | Ophthalmic lens | 株式会社目立康 | 2023-04-21 | — | — | CN | disclosed |
| CN-112334819-B | Ophthalmic device containing anionic agent | 株式会社实瞳 | 2022-10-14 | — | — | CN | disclosed |
| CN-1461325-A | Method of applying a polymeric lens coating | BAUSCH & LOMB (US) | 2003-12-10 | — | — | CN | disclosed |
| CN-1422298-A | Surface treatment of silicone medical device | BAUSCH & LOMB (US) | 2003-06-04 | — | — | CN | disclosed |
| JP-2002113089-A | POLYMER AND LENS FOR OCULUS USING IT | TORAY IND INC | 2002-04-16 | — | — | JP | disclosed |
| CN-1327002-A | Surface processed plastic product and surface processing method | TORAY INDUSTRIES (JP) | 2001-12-19 | — | — | CN | disclosed |
| CN-1173148-A | NCO-terminated vinyl telomers | CIBA GEIGY AG (CH) | 1998-02-11 | — | — | CN | disclosed |