SCHEMBL8994436

SCHEMBL8994436

CCCC[C](C)O[Si](C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.37
CES2 O00748 1/20 0.36
ALDH1A1 P00352 3/20 0.36
TP53 P04637 1/20 0.33
CA1 P00915 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28196127 0.73 CES1 (0.46) CES1CES2ALDH1A1TP53CA1
SCHEMBL4272897 0.70
SCHEMBL8688195 0.69
SCHEMBL3128838 0.67 CES1 (0.39) CES1CES2ALDH1A1TP53CA1
SCHEMBL7754248 0.67 CES2 (0.30) CES1CES2
SCHEMBL7754252 0.67 CES2 (0.30) CES1CES2
SCHEMBL19858487 0.67 DGKA (0.54) CES1CES2ALDH1A1
SCHEMBL6554418 0.65 DGKA (0.57) CES1CES2ALDH1A1
SCHEMBL2701285 0.65 DGKA (0.57) CES1CES2ALDH1A1
SCHEMBL2864499 0.65 CES2 (0.39) CES1CES2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5380900-A α-methylenecyclopentanone derivative and process for producing the same NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1995-01-10 US claimed
EP-0501426-B1 Alpha-methylenecyclopentanone derivative and process for producing the same NISSAN CHEMICAL IND LTD (JP) 1996-08-21 EP disclosed
US-5380900-A α-methylenecyclopentanone derivative and process for producing the same NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1995-01-10 US disclosed
EP-0501426-A1 Alpha-methylenecyclopentanone derivative and process for producing the same NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1992-09-02 EP disclosed