Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13387689 | 0.92 | MAPT (0.44) | MAPTPOLBALOX15L3MBTL1ALDH1A1 | |
| SCHEMBL13387618 | 0.84 | MAPT (0.47) | MAPTPOLBALDH1A1HSD17B10KDM4E | |
| SCHEMBL1577128 | 0.81 | MAPT (0.51) | MAPTPOLBALOX15L3MBTL1ALDH1A1 | |
| SCHEMBL22489117 | 0.80 | NPC1 (0.50) | MAPTPOLBALOX15ALDH1A1HSD17B10 | |
| SCHEMBL1576775 | 0.79 | FPR2 (0.44) | MAPTALDH1A1HSD17B10KDM4ELMNA | |
| SCHEMBL25314890 | 0.76 | ALDH1A1 (0.45) | MAPTPOLBALOX15L3MBTL1ALDH1A1 | |
| SCHEMBL29524269 | 0.76 | ALDH1A1 (0.45) | MAPTPOLBALOX15L3MBTL1ALDH1A1 | |
| SCHEMBL13387757 | 0.76 | MAPT (0.47) | MAPTPOLBALDH1A1HSD17B10KDM4E | |
| SCHEMBL14119926 | 0.75 | MAPT (0.50) | MAPTPOLBL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL10150650 | 0.75 | MAPT (0.53) | MAPTALOX15ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007112922-A1 | TRIMERIC, WATER-SOLUBLE AMINOPYRAZOLE COMPOUNDS HAVING AN EFFECT AGAINST NEURODEGENERATIVE DISEASES | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2007-10-11 | — | — | WO | disclosed |