SCHEMBL14397231

SCHEMBL14397231

c1cc(OCC2CCC3OC3C2)cc(OCC2CCC3O[C@H]3C2)c1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.49
TP53 P04637 1/20 0.49
CYP3A4 P08684 1/20 0.49
TSHR P16473 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
HIF1A Q16665 1/20 0.49
TLR4 O00206 2/20 0.45
TLR2 O60603 2/20 0.45
CHRNB4 P30926 1/20 0.41
CHRNA3 P32297 1/20 0.41
NR1H4 Q96RI1 1/20 0.41
CHRNB2 P17787 1/20 0.40
CHRNA4 P43681 1/20 0.40
ACACB O00763 1/20 0.39
ACACA Q13085 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12852056 1.00 ALDH1A1 (0.49) ALDH1A1TP53CYP3A4TSHRSMN1; SMN2
SCHEMBL14397530 0.92 ALDH1A1 (0.45) ALDH1A1TP53CYP3A4TSHRSMN1; SMN2
SCHEMBL20194411 0.90 ALDH1A1 (0.41) ALDH1A1TP53CYP3A4TSHRSMN1; SMN2
SCHEMBL5817830 0.90 GRM2 (0.44) ALDH1A1TP53CYP3A4TSHRSMN1; SMN2
SCHEMBL5749654 0.89 DRD2 (0.48)
SCHEMBL12855128 0.88 ALDH1A1 (0.39) ALDH1A1TP53CYP3A4TSHRSMN1; SMN2
SCHEMBL24936395 0.87 ALDH1A1 (0.41) ALDH1A1TP53CYP3A4TSHRSMN1; SMN2
SCHEMBL5819818 0.79 KDM4E (0.40)
SCHEMBL14817248 0.79 PARP15 (0.43)
SCHEMBL12730750 0.78 PARP15 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007114822-A1 THERMALLY CURABLE EPOXY-AMINE BARRIER SEALANTS NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 2007-10-11 WO disclosed