SCHEMBL20194411

SCHEMBL20194411

c1cc(OCC2CCC3NC3C2)cc(OCC2CCC3OC3C2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HIF1A Q16665 1/20 0.41
TLR4 O00206 2/20 0.39
TLR2 O60603 2/20 0.39
NR1H4 Q96RI1 1/20 0.36
CHRNB4 P30926 2/20 0.36
CHRNA3 P32297 2/20 0.36
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
HTR3A P46098 1/20 0.35
KCNH2 Q12809 1/20 0.35
PARP15 Q460N3 1/20 0.35
PARP10 Q53GL7 1/20 0.35
CHRNB2 P17787 1/20 0.35
CHRNA4 P43681 1/20 0.35
ACACB O00763 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14397231 0.90 ALDH1A1 (0.49) ALDH1A1TP53CYP3A4TSHRSMN1; SMN2
SCHEMBL12852056 0.90 ALDH1A1 (0.49) ALDH1A1TP53CYP3A4TSHRSMN1; SMN2
SCHEMBL14397530 0.83 ALDH1A1 (0.45) ALDH1A1TP53CYP3A4TSHRSMN1; SMN2
SCHEMBL5817830 0.81 GRM2 (0.44) ALDH1A1TP53CYP3A4TSHRSMN1; SMN2
SCHEMBL5749654 0.80 DRD2 (0.48)
SCHEMBL12855128 0.80 ALDH1A1 (0.39) ALDH1A1TP53CYP3A4TSHRSMN1; SMN2
SCHEMBL24936395 0.79 ALDH1A1 (0.41) ALDH1A1TP53CYP3A4TSHRSMN1; SMN2
SCHEMBL5819818 0.72 KDM4E (0.40) PARP15PARP10
SCHEMBL14817248 0.72 PARP15 (0.43) PARP15PARP10
SCHEMBL12730750 0.71 PARP15 (0.39) PARP15PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3327091-A1 EPOXY FUNCTIONAL COMPOSITION PROTECTING DYES FROM PHOTO-DEGRADATION AND CURED COATINGS PREPARED THEREFROM Essilor International (FR) 2018-05-30 EP disclosed