Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.39 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | CPA1 | P15085 | 2/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.31 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.31 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17773007 | 0.83 | ADAMTS4 (0.39) | SLC22A6CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL10065636 | 0.81 | MME (0.44) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL13851758 | 0.81 | MME (0.44) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL13851596 | 0.79 | ALDH1A1 (0.40) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL6374915 | 0.76 | ANPEP (0.47) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL3549858 | 0.75 | ALDH1A1 (0.37) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL6505335 | 0.73 | — | — | |
| SCHEMBL28097906 | 0.73 | LMNA (0.37) | ADRA1ATDP1 | |
| SCHEMBL10282635 | 0.73 | LMNA (0.37) | ADRA1ATDP1 | |
| SCHEMBL14369102 | 0.72 | MME (0.42) | MMEACECPA1ACE2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007111994-A2 | COMPOUNDS AND METHODS FOR TREATMENT OF DISORDERS ASSOCIATED WITH ER STRESS | SYNDEXA PHARMACEUTICALS CORPORATION (US) | 2007-10-04 | — | — | WO | disclosed |