Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14397205 | 0.91 | ALDH1A1 (0.42) | ALDH1A1HPGDGAANTRK1KDM4E | |
| SCHEMBL14397210 | 0.89 | GAA (0.45) | ALDH1A1HPGDGAANTRK1KDM4E | |
| SCHEMBL14396760 | 0.86 | ALDH1A1 (0.47) | ALDH1A1HPGDGAAKDM4EPOLB | |
| SCHEMBL14396752 | 0.84 | HPGD (0.44) | ALDH1A1HPGDGAANTRK1KDM4E | |
| SCHEMBL14396755 | 0.83 | CHRM2 (0.44) | ALDH1A1HPGDGAAKDM4EPOLB | |
| SCHEMBL16814655 | 0.80 | ALDH1A1 (0.44) | ALDH1A1HPGDGAANTRK1KDM4E | |
| SCHEMBL14397212 | 0.78 | ALDH1A1 (0.40) | ALDH1A1HPGDGAAKDM4EPOLB | |
| SCHEMBL16794891 | 0.77 | NTRK1 (0.41) | ALDH1A1HPGDGAANTRK1KDM4E | |
| SCHEMBL1002968 | 0.76 | NTRK1 (0.58) | ALDH1A1HPGDGAANTRK1KDM4E | |
| SCHEMBL29469528 | 0.76 | NTRK1 (0.58) | ALDH1A1HPGDGAANTRK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007117289-A2 | METHODS FOR TREATING OR PREVENTING ERECTILE DYSFUNCTION OR URINARY INCONTINENCE | INOTEK PHARMACEUTICALS CORPORATION (US) | 2007-10-18 | — | — | WO | disclosed |