Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14397210 | 0.93 | GAA (0.45) | ALDH1A1HPGDGAAKDM4EHSD17B10 | |
| SCHEMBL14397606 | 0.91 | ALDH1A1 (0.51) | ALDH1A1HPGDGAAKDM4ENTRK1 | |
| SCHEMBL14396760 | 0.83 | ALDH1A1 (0.47) | ALDH1A1HPGDGAAKDM4EHSD17B10 | |
| SCHEMBL14396752 | 0.81 | HPGD (0.44) | ALDH1A1HPGDGAAKDM4EHSD17B10 | |
| SCHEMBL14396755 | 0.80 | CHRM2 (0.44) | ALDH1A1HPGDGAAKDM4EHTT | |
| SCHEMBL14397212 | 0.76 | ALDH1A1 (0.40) | ALDH1A1HPGDGAAKDM4EHSD17B10 | |
| SCHEMBL16814655 | 0.72 | ALDH1A1 (0.44) | ALDH1A1HPGDGAAKDM4ENTRK1 | |
| SCHEMBL19364971 | 0.71 | KDM4E (0.47) | ALDH1A1HPGDGAAKDM4EHSD17B10 | |
| SCHEMBL16794891 | 0.70 | NTRK1 (0.41) | ALDH1A1HPGDGAAKDM4EHSD17B10 | |
| SCHEMBL5344249 | 0.68 | DAO (0.43) | ALDH1A1HPGDGAAP2RX4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007117289-A2 | METHODS FOR TREATING OR PREVENTING ERECTILE DYSFUNCTION OR URINARY INCONTINENCE | INOTEK PHARMACEUTICALS CORPORATION (US) | 2007-10-18 | — | — | WO | disclosed |