Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14396760 | 0.86 | ALDH1A1 (0.47) | HPGDALDH1A1KDM4ENPSR1MEN1 | |
| SCHEMBL14397606 | 0.84 | ALDH1A1 (0.51) | HPGDALDH1A1SMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL14396755 | 0.83 | CHRM2 (0.44) | HPGDALDH1A1KDM4ENPSR1GAA | |
| SCHEMBL14397212 | 0.81 | ALDH1A1 (0.40) | HPGDALDH1A1KDM4ENPSR1KMT2A | |
| SCHEMBL14397205 | 0.81 | ALDH1A1 (0.42) | HPGDALDH1A1SMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL14397210 | 0.79 | GAA (0.45) | HPGDALDH1A1KDM4ENPSR1MEN1 | |
| SCHEMBL8076307 | 0.66 | KMT2A (0.47) | HPGDALDH1A1SMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL9395651 | 0.66 | ALDH1A1 (0.50) | HPGDALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL8076309 | 0.66 | KMT2A (0.47) | HPGDALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL5344249 | 0.66 | DAO (0.43) | HPGDALDH1A1GAAPOLBP2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007117289-A2 | METHODS FOR TREATING OR PREVENTING ERECTILE DYSFUNCTION OR URINARY INCONTINENCE | INOTEK PHARMACEUTICALS CORPORATION (US) | 2007-10-18 | — | — | WO | disclosed |