Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 7/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 6/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14399395 | 0.93 | PPARA (0.45) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL5326681 | 0.89 | CNR1 (0.48) | PPARACNR1ACACBPPARGPPARD | |
| SCHEMBL14397270 | 0.85 | LMNA (0.49) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL14399419 | 0.83 | PPARA (0.42) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL14399345 | 0.83 | PPARA (0.45) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL14399347 | 0.81 | CTSS (0.48) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL5329478 | 0.81 | PPARA (0.54) | PPARACNR1PPARGPPARD | |
| SCHEMBL5331315 | 0.80 | CDK2 (0.52) | ACACBDDR1 | |
| SCHEMBL7977777 | 0.75 | PPARA (0.68) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL5324085 | 0.74 | PPARA (0.48) | PPARACYP1A2CYP3A4CNR1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118964-A1 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007118963-A2 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |