Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.45 |
| ▸ | PPARG | P37231 | 12/20 | 0.45 |
| ▸ | PPARD | Q03181 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5323469 | 0.88 | MEN1 (0.48) | PPARAPPARGPPARDALDH1A1MEN1 | |
| SCHEMBL5321332 | 0.85 | ALDH1A1 (0.59) | PPARAPPARGPPARDALDH1A1MEN1 | |
| SCHEMBL14397757 | 0.85 | ALDH1A1 (0.43) | PPARAPPARGPPARDALDH1A1MEN1 | |
| SCHEMBL5326619 | 0.85 | ALDH1A1 (0.42) | PPARAPPARGPPARDALDH1A1MEN1 | |
| SCHEMBL5326505 | 0.84 | NR1H4 (0.49) | PPARAPPARGPPARDALDH1A1MEN1 | |
| SCHEMBL14397275 | 0.84 | NR1H4 (0.49) | PPARAPPARGPPARDALDH1A1MEN1 | |
| SCHEMBL5329406 | 0.83 | PPARA (0.54) | PPARAPPARGPPARDALDH1A1 | |
| SCHEMBL14398214 | 0.82 | MEN1 (0.49) | PPARAPPARGPPARDALDH1A1MEN1 | |
| SCHEMBL5328239 | 0.81 | ACACB (0.42) | PPARAPPARGPPARDALDH1A1MEN1 | |
| SCHEMBL5326276 | 0.79 | ROCK2 (0.44) | PPARAPPARGPPARDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118964-A1 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |