Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5323469 | 0.86 | MEN1 (0.48) | ACACBALDH1A1MEN1KMT2APPARA | |
| SCHEMBL5325161 | 0.85 | ACACB (0.48) | ACACBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5326505 | 0.84 | NR1H4 (0.49) | ACACBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14397275 | 0.84 | NR1H4 (0.49) | ACACBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14397757 | 0.84 | ALDH1A1 (0.43) | ACACBALDH1A1MEN1KMT2APPARA | |
| SCHEMBL5321332 | 0.84 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2MEN1KMT2APPARA | |
| SCHEMBL14398214 | 0.83 | MEN1 (0.49) | ALDH1A1MEN1KMT2APPARAPPARG | |
| SCHEMBL14397756 | 0.81 | PPARA (0.45) | ALDH1A1MEN1KMT2APPARAPPARG | |
| SCHEMBL14399160 | 0.81 | PPARG (0.43) | ACACBALDH1A1PPARAPPARGCNR1 | |
| SCHEMBL5326619 | 0.80 | ALDH1A1 (0.42) | ACACBALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118964-A1 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007118964-A1 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |