Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21843252 | 0.92 | BRD4 (0.56) | KDM4EALOX15L3MBTL1MAPTBRD4 | |
| SCHEMBL26081236 | 0.86 | BRD4 (0.51) | KDM4EALOX15L3MBTL1MAPTBRD4 | |
| SCHEMBL750492 | 0.82 | BRD4 (0.51) | KDM4EALOX15L3MBTL1MAPTBRD4 | |
| SCHEMBL24485539 | 0.81 | MAPT (0.48) | KDM4EALOX15L3MBTL1MAPTBRD4 | |
| SCHEMBL159285 | 0.81 | BRD4 (0.50) | KDM4EALOX15L3MBTL1MAPTBRD4 | |
| SCHEMBL699240 | 0.80 | LMNA (0.51) | KDM4EL3MBTL1MAPTALDH1A1TP53 | |
| SCHEMBL18043964 | 0.80 | BRD4 (0.57) | KDM4EALOX15L3MBTL1MAPTBRD4 | |
| SCHEMBL11732040 | 0.79 | MAPT (0.49) | KDM4EALOX15L3MBTL1MAPTBRD4 | |
| SCHEMBL29642902 | 0.79 | RAB9A (0.55) | KDM4EL3MBTL1MAPTBRD4ALDH1A1 | |
| SCHEMBL23611731 | 0.79 | BRD4 (0.49) | KDM4EALOX15L3MBTL1MAPTBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007117180-A1 | AZAHETEROCYCLES, COMBINATORY LIBRARY, FOCUSED LIBRARY, PHARMACEUTICAL COMPOSITION AND METHODS FOR THE PRODUCTION THEREOF | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE' LTD. (RU) | 2007-10-18 | — | — | WO | disclosed |