Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | GBA1 | P04062 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3979132 | 1.00 | RAB9A (0.55) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| Thiophene SCHEMBL8806427 | 0.89 | RAB9A (0.47) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL21843252 | 0.86 | BRD4 (0.56) | NPC1KDM4EALDH1A1L3MBTL1BRD4 | |
| SCHEMBL30811269 | 0.82 | KDM4E (0.42) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL26081236 | 0.81 | BRD4 (0.51) | NPC1KDM4EALDH1A1L3MBTL1BRD4 | |
| SCHEMBL750492 | 0.81 | BRD4 (0.51) | NPC1KDM4EALDH1A1L3MBTL1BRD4 | |
| SCHEMBL14398367 | 0.79 | KDM4E (0.60) | RAB9ANPC1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL159285 | 0.79 | BRD4 (0.50) | NPC1KDM4EALDH1A1L3MBTL1BRD4 | |
| SCHEMBL1761085 | 0.79 | ALDH1A1 (0.49) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL32682741 | 0.79 | NPSR1 (0.48) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022134043-A1 | GLYCINE N-METHYLTRANSFERASE ENHANCER, PREPARATION METHOD THEREFOR AND USE THEREOF | 高雄医学大学 | 2022-06-30 | — | — | WO | disclosed |