Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.71 |
| ▸ | MEN1 | O00255 | 4/20 | 0.71 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.62 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5323935 | 0.92 | ALDH1A1 (0.66) | ALDH1A1KMT2AMEN1TAS1R3TAS1R1 | |
| SCHEMBL9169977 | 0.91 | KMT2A (0.79) | ALDH1A1KMT2AMEN1TAS1R3TAS1R1 | |
| SCHEMBL6297588 | 0.83 | ALDH1A1 (0.81) | ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL5322502 | 0.82 | ALDH1A1 (0.68) | ALDH1A1KMT2AMEN1L3MBTL1POLB | |
| SCHEMBL9829926 | 0.82 | KMT2A (0.65) | KMT2AMEN1L3MBTL1POLB | |
| SCHEMBL9829918 | 0.82 | KMT2A (0.65) | KMT2AMEN1L3MBTL1POLB | |
| SCHEMBL28901354 | 0.81 | KMT2A (0.77) | ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL29924236 | 0.81 | KMT2A (0.77) | ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL29924325 | 0.81 | KMT2A (0.77) | ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL28901353 | 0.81 | KMT2A (0.77) | ALDH1A1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007120083-A1 | THE USE OF CARBOXAMIDE DERIVATIVES IN THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF INFLAMMATORY, ALLERGIC AND DERMATOLOGICAL CONDITIONS | ASTRAZENECA AB (SE) | 2007-10-25 | — | — | WO | disclosed |