Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.79 |
| ▸ | MEN1 | O00255 | 5/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14399043 | 0.91 | ALDH1A1 (0.73) | KMT2AMEN1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL5323935 | 0.84 | ALDH1A1 (0.66) | KMT2AMEN1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL9829926 | 0.83 | KMT2A (0.65) | KMT2AMEN1MAPTCYP3A4CYP2D6 | |
| SCHEMBL9829918 | 0.83 | KMT2A (0.65) | KMT2AMEN1MAPTCYP3A4CYP2D6 | |
| SCHEMBL11808978 | 0.81 | KMT2A (0.65) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL8259636 | 0.81 | KMT2A (0.62) | KMT2AMEN1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL25306507 | 0.78 | ALDH1A1 (0.72) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL9164083 | 0.78 | HTT (0.78) | KMT2AMEN1MAPTCYP3A4CYP2D6 | |
| SCHEMBL9164074 | 0.78 | HTT (0.78) | KMT2AMEN1MAPTCYP3A4CYP2D6 | |
| SCHEMBL19427446 | 0.78 | EPHX2 (0.80) | KMT2AMEN1ALDH1A1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443606-B1 | 4-(4-alkoxyphenyl)-2-butylamine derivatives and process therefor | SHIONOGI & CO (JP) | 1995-05-10 | — | — | EP | disclosed |
| US-5073648-A | Intermediates for dopamine derivatives | SHIONOGI & CO., LTD. (JP) | 1991-12-17 | — | — | US | disclosed |
| EP-0443606-A2 | 4-(4-alkoxyphenyl)-2-butylamine derivatives and process therefor | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-3987200-A | INOTROPIC AGENTS, 3,4-DIHYDROXY-PHENYL-ALKYL PHENETHYLAMINE | ELI LILLY AND COMPANY (US) | 1976-10-19 | — | — | US | disclosed |