Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 9/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14399180 | 0.85 | CNR1 (0.41) | NPC1RAB9AMEN1KMT2AACACB | |
| SCHEMBL5321493 | 0.83 | PSMB5 (0.46) | MEN1KMT2AACACB | |
| SCHEMBL5321488 | 0.83 | PSMB5 (0.46) | MEN1KMT2AACACB | |
| SCHEMBL5323214 | 0.83 | PSMB5 (0.46) | MEN1KMT2AACACB | |
| SCHEMBL5324018 | 0.79 | MAPT (0.52) | NPC1RAB9AMEN1KMT2AACACB | |
| SCHEMBL5321673 | 0.77 | KDM4E (0.45) | NPC1RAB9AMEN1KMT2AACACB | |
| SCHEMBL14397665 | 0.77 | KMT2A (0.60) | NPC1RAB9AMEN1KMT2AKDR | |
| SCHEMBL5325964 | 0.73 | POLB (0.61) | NPC1RAB9AMEN1KMT2AGAA | |
| SCHEMBL5320725 | 0.73 | PSMB5 (0.45) | MEN1KMT2ALMNA | |
| SCHEMBL11173723 | 0.73 | TPH1 (0.47) | MEN1KMT2AACACBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118963-A2 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |