Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24862861 | 0.90 | POLB (0.74) | POLBNPC1RAB9AGAALMNA | |
| SCHEMBL24862943 | 0.84 | NPC1 (0.50) | POLBNPC1RAB9AOPRM1OPRD1 | |
| SCHEMBL24862953 | 0.83 | ALDH1A1 (0.51) | NPC1RAB9AOPRM1OPRD1OPRK1 | |
| SCHEMBL24862961 | 0.83 | GFER (0.58) | POLBNPC1RAB9AOPRM1OPRD1 | |
| SCHEMBL24862860 | 0.81 | CAPN1 (0.57) | POLBNPC1RAB9AGAAALDH1A1 | |
| SCHEMBL10330510 | 0.81 | POLB (0.65) | POLBNPC1RAB9AGAALMNA | |
| SCHEMBL5324074 | 0.80 | CDK2 (0.54) | NPC1RAB9A | |
| SCHEMBL5328209 | 0.80 | CTSS (0.56) | POLBNPC1RAB9AOPRM1OPRD1 | |
| SCHEMBL5331315 | 0.80 | CDK2 (0.52) | POLBNPC1RAB9A | |
| SCHEMBL24862899 | 0.80 | RAB9A (0.67) | NPC1RAB9AOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102193-B1 | ANTIBACTERIAL AGENTS: N(ALPHA)-AROYL-N-ARYL-PHENYLALANINAMIDES | UNIV RUTGERS (US) | 2023-01-11 | — | — | EP | disclosed |
| WO-2007118963-A2 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007118964-A1 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |