Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.60 |
| ▸ | MEN1 | O00255 | 7/20 | 0.60 |
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | POLB | P06746 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5327174 | 0.84 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1HTTNPSR1 | |
| SCHEMBL14398214 | 0.84 | MEN1 (0.49) | KMT2AMEN1NPC1POLBRAB9A | |
| SCHEMBL5324896 | 0.83 | NR1H4 (0.55) | KMT2AMEN1ALDH1A1ACACB | |
| SCHEMBL5325179 | 0.83 | NR1H4 (0.55) | KMT2AMEN1ALDH1A1ACACB | |
| SCHEMBL5326665 | 0.83 | NR1H4 (0.55) | KMT2AMEN1ALDH1A1ACACB | |
| SCHEMBL5325174 | 0.81 | ALDH1A1 (0.70) | RAB9AALDH1A1LMNAACACBL3MBTL1 | |
| SCHEMBL14398212 | 0.79 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1HTTACACB | |
| SCHEMBL5325161 | 0.79 | ACACB (0.48) | KMT2AMEN1ALDH1A1ACACBL3MBTL1 | |
| SCHEMBL5325964 | 0.77 | POLB (0.61) | KMT2AMEN1NPC1POLBRAB9A | |
| SCHEMBL14399343 | 0.77 | NPC1 (0.42) | KMT2AMEN1NPC1RAB9AKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118964-A1 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |