Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | GFER | P55789 | 1/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14399909 | 0.87 | GFER (0.63) | KMT2ASMN1; SMN2GFERRECQLGABRP | |
| SCHEMBL14404103 | 0.84 | SMN1; SMN2 (0.47) | KMT2ASMN1; SMN2GFERGAAMAPT | |
| SCHEMBL9853492 | 0.81 | SMN1; SMN2 (0.77) | KMT2ASMN1; SMN2GFERRECQLNOS2 | |
| SCHEMBL11459872 | 0.81 | SMN1; SMN2 (1.00) | KMT2ASMN1; SMN2GFERRECQLNOS2 | |
| SCHEMBL12253477 | 0.81 | SMN1; SMN2 (1.00) | KMT2ASMN1; SMN2GFERRECQLNOS2 | |
| SCHEMBL14371157 | 0.80 | ALDH1A1 (0.47) | KMT2ASMN1; SMN2GFERGABRPGABRD | |
| SCHEMBL14099960 | 0.77 | SMN1; SMN2 (0.65) | KMT2ASMN1; SMN2GFERRECQLGABRP | |
| SCHEMBL14400133 | 0.76 | NOS2 (0.46) | KMT2ASMN1; SMN2GFERRECQLNOS2 | |
| SCHEMBL11527268 | 0.76 | SMN1; SMN2 (0.63) | KMT2ASMN1; SMN2GFERRECQLGABRP | |
| SCHEMBL11527264 | 0.76 | SMN1; SMN2 (0.63) | KMT2ASMN1; SMN2GFERRECQLGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070238700-A1 | N-PHENYL-1,1,1-TRIFLUOROMETHANESULFONAMIDE HYDRAZONE DERIVATIVE COMPOUNDS AND THEIR USAGE IN CONTROLLING PARASITES | SCHERING-PLOUGH LTD. (CH) | 2007-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238700-A1 | N-PHENYL-1,1,1-TRIFLUOROMETHANESULFONAMIDE HYDRAZONE DERIVATIVE COMPOUNDS AND THEIR USAGE IN CONTROLLING PARASITES | NAT1, NGLY1, ELANE | KMT2A 1645/4885SMN1; SMN2 2540/4885GFER 2861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.