Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | GFER | P55789 | 1/20 | 0.77 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | FADS1 | O60427 | 1/20 | 0.41 |
| ▸ | S100B | P04271 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12253477 | 0.87 | SMN1; SMN2 (1.00) | SMN1; SMN2KMT2AGFERRECQLFADS1 | |
| SCHEMBL11459872 | 0.87 | SMN1; SMN2 (1.00) | SMN1; SMN2KMT2AGFERRECQLFADS1 | |
| SCHEMBL14399951 | 0.81 | KMT2A (0.68) | SMN1; SMN2KMT2AGFERRECQLFADS1 | |
| SCHEMBL8316276 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2KMT2AGFERRECQLFADS1 | |
| SCHEMBL14399954 | 0.79 | KMT2A (0.65) | SMN1; SMN2KMT2AGFERRECQLFADS1 | |
| SCHEMBL14100042 | 0.79 | SMN1; SMN2 (0.65) | SMN1; SMN2KMT2AGFERRECQLFADS1 | |
| SCHEMBL14099960 | 0.79 | SMN1; SMN2 (0.65) | SMN1; SMN2KMT2AGFERRECQLGRIN2B | |
| SCHEMBL9853483 | 0.78 | MAPT (0.53) | SMN1; SMN2KMT2AGFERALOX15CYP3A4 | |
| SCHEMBL9853569 | 0.78 | GFER (0.63) | SMN1; SMN2KMT2AGFERRECQLFADS1 | |
| SCHEMBL14399909 | 0.78 | GFER (0.63) | SMN1; SMN2KMT2AGFERRECQLFADS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433526-A1 | Medicine for the treatment of heart-circulatory illnesses, of arrhythmics in particular | Richter, Peter, Prof. Dr.sc.nat. (DE) | 1991-06-26 | — | — | EP | disclosed |