Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1760843 | 0.80 | TRPV4 (0.42) | ALDH1A1SMN1; SMN2KDM4EGAAKEAP1 | |
| SCHEMBL2980809 | 0.79 | KEAP1 (0.42) | ALDH1A1SMN1; SMN2KEAP1KMT2AMEN1 | |
| SCHEMBL14401691 | 0.76 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2GLAKDM4EKMT2A | |
| SCHEMBL23568566 | 0.74 | KEAP1 (0.47) | ALDH1A1KEAP1KMT2AMEN1POLB | |
| SCHEMBL4973829 | 0.74 | KEAP1 (0.42) | ALDH1A1SMN1; SMN2KDM4EKEAP1KMT2A | |
| SCHEMBL14271818 | 0.73 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2KDM4EGAAKEAP1 | |
| Ammonia Solution, Strong SCHEMBL2980807 | 0.73 | KEAP1 (0.46) | ALDH1A1KEAP1KMT2AMEN1POLB | |
| SCHEMBL13592488 | 0.73 | KEAP1 (0.46) | ALDH1A1SMN1; SMN2KDM4EGAAKEAP1 | |
| SCHEMBL12626886 | 0.71 | KEAP1 (0.38) | ALDH1A1SMN1; SMN2KDM4EGAAKEAP1 | |
| SCHEMBL23569845 | 0.70 | KEAP1 (0.43) | ALDH1A1GAAKEAP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070248594-A1 | CXCR1 AND CXCR2 CHEMOKINE ANTAGONISTS | SCHERING CORPORATION | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070248594-A1 | CXCR1 AND CXCR2 CHEMOKINE ANTAGONISTS | CXCR1, CXCR2, CXCR5 | ALDH1A1 1045/4885SMN1; SMN2 4668/4885GLA 3766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.