Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL158558 | 0.85 | — | — | |
| SCHEMBL159682 | 0.83 | ALDH1A1 (0.34) | KDM4EALDH1A1 | |
| SCHEMBL175588 | 0.83 | KDM4E (0.40) | MAPTKDM4ELMNAKMT2AALDH1A1 | |
| SCHEMBL12302082 | 0.81 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL12330842 | 0.78 | TRPV1 (0.39) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL14537548 | 0.75 | KDM4E (0.36) | MAPTKDM4EKMT2AALDH1A1 | |
| SCHEMBL1443416 | 0.74 | ALDH1A1 (0.38) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL1444213 | 0.73 | NOTUM (0.43) | MAPTKDM4ELMNAKMT2AALDH1A1 | |
| SCHEMBL15675519 | 0.73 | ALDH1A1 (0.52) | KMT2AALDH1A1 | |
| SCHEMBL15675309 | 0.72 | CA1 (0.38) | MAPTKDM4EMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8350099-B2 | Fluorovinyl ether functionalized aromatic diesters, derivatives thereof, and process for the preparation thereof | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-01-08 | — | — | US | disclosed |
| US-8350099-B2 | Fluorovinyl ether functionalized aromatic diesters, derivatives thereof, and process for the preparation thereof | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-01-08 | — | — | US | disclosed |
| EP-2473474-A2 | FLUOROETHER FUNCTIONALIZED AROMATIC DIESTERS AND DERIVATIVES THEREOF | E. I. du Pont de Nemours and Company (US) | 2012-07-11 | — | — | EP | disclosed |
| US-20110218353-A1 | FLUOROVINYL ETHER FUNCTIONALIZED AROMATIC DIESTERS, DERIVATIVES THEREOF, AND PROCESS FOR THE PREPARATION THEREOF | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-09-08 | — | — | US | disclosed |
| US-20110218353-A1 | FLUOROVINYL ETHER FUNCTIONALIZED AROMATIC DIESTERS, DERIVATIVES THEREOF, AND PROCESS FOR THE PREPARATION THEREOF | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-09-08 | — | — | US | disclosed |
| WO-2011028767-A2 | FLUOROETHER FUNCTIONALIZED AROMATIC DIESTERS AND DERIVATIVES THEREOF | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110218353-A1 | FLUOROVINYL ETHER FUNCTIONALIZED AROMATIC DIESTERS, DERIVATIVES THEREOF, AND PROCESS FOR THE PREPARATION THEREOF | PFAS, PAH, AFF4 | MAPT 1580/4885KDM4E 50/4885MEN1 1659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.